Article
Cooperation between the thyroid hormone receptor TRalpha1 and the WNT pathway in the induction of intestinal tumorigenesis.
Gastroenterology - 1 May 2010
Kress Elsa, Skah Seham, Sirakov Maria, Nadjar Julien, Gadot Nicolas, Scoazec Jean-Yves, Samarut Jacques, Plateroti Michelina
Abstract excerpt
BACKGROUND & AIMS: Colorectal tumorigenesis is a multistep process involving the alteration of oncogenes and tumor suppressor genes, leading to the deregulation of molecular pathways that govern intestinal homeostasis. We have previously shown that the thyroid hormone receptor alpha1 (TRalpha1) c...
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