Article
Association of the 894G>T polymorphism in the endothelial nitric oxide synthase gene with risk of venous thromboembolism in Chinese population.
Thrombosis research - 1 Apr 2011
Li Yan-Yan, Zhai Zhen-Guo, Yang Yuan-Hua, Pang Bao-Sen, Wang He-Yao, Zhang Wei, Zhao Lan, Wang Jun, Wang Chen
Abstract excerpt
INTRODUCTION: Endothelium derived nitric oxide (NO) is a key mediator of vascular homeostasis. Endothelial nitric oxide synthase (eNOS) gene, by affecting the expression and functional activity of the eNOS enzyme, thereby reducing NO availability, may be implicated in venous thromboembolism (VTE). We investigated the eNOS G894T polymorphism in VTE patients in the Chinese population. MATERIALS AND METHODS: A...
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