Article
Endothelial Nitric Oxide Synthase Gene Polymorphisms Increase Risk of Deep Vein Thrombosis by Altering Homocysteine Levels.
Clinical laboratory - 1 Mar 2022
Akhter Mohammad S, Biswas Arijit, Iqbal Johar, Hamali Hassan A, Mobarki Abdullah A, Abdullah Saleh M, Dobie Gasim, Saxena Renu
Abstract excerpt
BACKGROUND: Deep Vein Thrombosis (DVT) is a multicausal disease involving both acquired as well as genetic factors. Nitric oxide is an influential endogenous factor having its role in the development of deep vein thrombosis. It maintains the vascular integrity and any alterations in its levels may lead to a thrombotic event. It may also modulate homocysteine metabolism to cause hyperhomocysteinemia, which is a...
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