Article
Association between IL2/IL21 and SH2B3 polymorphisms and risk of celiac disease: a meta-analysis.
Genetics and molecular research : GMR - 27 Oct 2015
Guo C C, Huang W H, Zhang N, Dong F, Jing L P, Liu Y, Ye X G, Xiao D, Ou M L, Zhang B H, Wang M, Liang W K, Yang G, Jing C X
Abstract excerpt
Celiac disease (CD) is a common autoimmune disorder characterized by heightened immunological response to ingested gluten. Certain gene polymorphisms of IL2/IL21 (rs6822844 and rs6840978) and SH2B3 (rs3184504) may influence susceptibility to CD, although the effects remain unclear. We performed a meta-analysis of the associations between rs6822844, rs6840978, and polymorphisms and CD risk. PubMed,...