Article
The segregation of cancer-causing genes in human populations.
Mutation research - 1 Apr 1991
Schull W J
Abstract excerpt
Cancer can arise through genetic damage of a variety of sorts, including recessive and dominant mutations, large chromosomal rearrangements, and the inability of cells to repair damaged DNA. Many of these events can be studied by standard methods of genetic analysis and thereby furnish the means to localize the gene to a specific region in the human genome. However, conventional methods of segregation analysis...
Topics
- Family
- Gene Expression Regulation, Neoplastic
- Genetic Predisposition to Disease
- Genotype
- Humans
- Mutation
- Neoplasms