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Article

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.

Blood - 13 May 2010

Uhrin Pavel, Zaujec Jan, Breuss Johannes M, Olcaydu Damla, Chrenek Peter, Stockinger Hannes, Fuertbauer Elke, Moser Markus, Haiko Paula, Fässler Reinhard, Alitalo Kari, Binder Bernd R, Kerjaschki Dontscho

Abstract excerpt

During embryonic development, lymph sacs form from the cardinal vein, and sprout centrifugally to form mature lymphatic networks. Separation of the lymphatic from the blood circulation by a hitherto unknown mechanism is essential for the homeostatic function of the lymphatic system. O-glycans on...

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Source

Identifiers

PMID: 20110424
DOI: 10.1182/blood-2009-04-216069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20110424-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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