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Article

Polymorphisms in the estrogen receptor genes are associated with hip fractures in Chinese.

Bone - 1 Nov 2008

Wang Jin-Tang, Guo Yan, Yang Tie-Lin, Xu Xiang-Hong, Dong Shan-Shan, Li Meng, Li Tian-Qing, Chen Yuan, Deng Hong-Wen

Abstract excerpt

INTRODUCTION: Hip fractures (HF) are a major cause of public health burden with strong genetic determination. However, the true causal genes remain largely unknown. MATERIALS AND METHODS: Based on the important biological role of estrogens in bone homeostasis, this study aimed to investigate whether the estrogen receptor genes, ESR1 and ESR2, affect the onset of HF in 700 elderly Chinese subjects (350 with...

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Source

Identifiers

PMID: 18678289
DOI: 10.1016/j.bone.2008.07.001

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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