Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Polymorphisms in Estrogen Receptor Genes (ESR1 and ESR2) with Osteoporosis and Fracture-Involvement of Comorbidities and Epistasis.

DNA and cell biology - 1 Apr 2022

García-Rojas M Davidnia, Palma-Cordero Grecia, Martínez-Ramírez Celeste O, Ponce de León-Suárez Valeria, Valdés-Flores Margarita, Castro-Hernández Clementina, Rubio-Lightbourn Julieta, Hernández-Zamora Edgar, Reyes-Maldonado Elba, Velázquez-Cruz Rafael, Barredo-Prieto Blanca, Casas-Avila Leonora

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) in the ESR1/ESR2 genes play a role in osteoporosis (OP). Our objective was to determine associations of polymorphisms in ESR genes with OP and fracture, SNP-SNP interactions, and involvement of comorbidities. We analyzed 170 Mexican osteoporotic women (FNOP), 173 with hip fracture (HFx), and 210 controls. The SNPs, ESR1 rs2234693CC, rs851982CC and rs1999805AA, were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epistasis, Genetic
Share to Estrogen and related hormone effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

Share to Estrogen Receptor beta

Share to Genetic Predisposition to Disease

Share to Osteoporosis

Share to Polymorphism, Single Nucleotide

Share to Receptors, Estrogen

Source

Identifiers

PMID: 35285722
DOI: 10.1089/dna.2021.1165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Polymorphisms in Estrogen Receptor Genes (ESR1 and ESR2) with Osteoporosis and Fracture-Involvement of Comorbidities and Epistasis.PMID 35285722Read ↗

Polymorphisms in the estrogen receptor genes are associated with hip fractures in Chinese.Semantic proximity Read ↗

Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women.Semantic proximity Read ↗

Association of ESR1 and ESR2 Polymorphisms with Osteoporosis: A Meta-Analysis from 36 Studies.Semantic proximity Read ↗

Association of ESR1 polymorphism rs2234693 and rs9340799 with postmenopausal osteoporosis in a Chinese population.Semantic proximity Read ↗

Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes.Semantic proximity Read ↗

Association of ESR1 polymorphism rs2234693 and rs9340799 with Postmenopausal osteoporosis in a Chinese PopulationSemantic proximity Read ↗

Estrogen Receptor Gene Polymorphisms and the Genetics of Osteoporosis: A HuGE ReviewSemantic proximity Read ↗

Relationship between estrogen receptor 1 gene polymorphisms and postmenopausal osteoporosis of the spine in Chinese women.Semantic proximity Read ↗

Relationship between Coffee Consumption and Osteoporosis Risk Determined by the ESR1 Polymorphism rs2982573.Semantic proximity Read ↗

Association between the ESR1 and ESR2 polymorphisms and osteoporosis risk: An updated meta-analysis.Semantic proximity Read ↗

Interaction between ESRα polymorphisms and environmental factors in osteoporosis.Semantic proximity Read ↗

Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.