Article
Genetic and epigenetic factors affecting blastomere fragmentation in two-cell stage mouse embryos.
Biology of reproduction - 1 Oct 2001
Hawes S M, Gie Chung Y, Latham K E
Abstract excerpt
We report here that mouse embryos can exhibit a significant incidence of blastomere fragmentation at the two-cell stage. The incidence of this is influenced by both the maternal and paternal genotype. Embryos from C57BL/6 mothers exhibit a very low incidence of fragmentation at the two-cell stage in crosses involving males of C57BL/6, DBA/2, AKR/J, or SJL strains but exhibit a significantly increased incidence of...
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