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Genomic RNA profiling and the programme controlling preimplantation mammalian development

29 Nov 2008

Abstract excerpt

Preimplantation development shifts from a maternal to embryonic programme rapidly after fertilization. Although the majority of oogenetic products are lost during the maternal to embryonic transition (MET), several do survive this interval to contribute directly to supporting preimplantation development. Embryonic genome activation (EGA) is characterized by the transient expression of several genes that are...

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PMID: 19043080
DOI: 10.1093/molehr/gan063

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