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Article

Escherichia coli rpoB mutants have increased evolvability in proportion to their fitness defects.

Molecular biology and evolution - 1 Jun 2010

Barrick Jeffrey E, Kauth Mark R, Strelioff Christopher C, Lenski Richard E

Abstract excerpt

Evolvability is the capacity of an organism or population for generating descendants with increased fitness. Simulations and comparative studies have shown that evolvability can vary among individuals and identified characteristics of genetic architectures that can promote evolvability. However, little is known about how the evolvability of biological organisms typically varies along a lineage at each mutational...

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Identifiers

PMID: 20106907
DOI: 10.1093/molbev/msq024
PMCID: PMC2872623

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Source receipt: pubmed, retrieved 7 Sept 2026.

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