Evolvability-enhancing mutations in the fitness landscapes of an RNA and a protein.

Abstract excerpt

Can evolvability-the ability to produce adaptive heritable variation-itself evolve through adaptive Darwinian evolution? If so, then Darwinian evolution may help create the conditions that enable Darwinian evolution. Here I propose a framework that is suitable to address this question with available experimental data on adaptive landscapes. I introduce the notion of an evolvability-enhancing mutation, which...

Topics

• RNA
• Mutation
• Evolution, Molecular
• Models, Genetic
• Biological Evolution
• Genetic Fitness