Article
Identification of a new bovine MHC class II DRB allele by nucleotide sequencing and an analysis of phylogenetic relationships.
Biochemical and biophysical research communications - 26 Apr 1995
Aida Y, Niimi M, Asahina M, Okada K, Nakai Y, Ogimoto K
Abstract excerpt
Three overlapping cDNA clones coding for the bovine major histocompatibility complex (MHC) class II DR beta chain were isolated. A clone NR1 encoded a primary translated product of 266 amino acids, 29 of which were deduced to form a signal peptide and 237 to form the mature polypeptide. The protein predicted from this cDNA appeared to have all the features expected of an expressed MHC class II molecule....
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cattle
- DNA Primers
- DNA, Complementary
- Dogs
- Genes, MHC Class II
- Histocompatibility Antigens Class II
- Humans