Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.

doi:10.1016/j.ajhg.2009.12.014

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Article

Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.

American journal of human genetics - 12 Feb 2010

Kung Annie W C, Xiao Su-Mei, Cherny Stacey, Li Gloria H Y, Gao Yi, Tso Gloria, Lau Kam S, Luk Keith D K, Liu Jian-min, Cui Bin, Zhang Min-Jia, Zhang Zhen-lin, He Jin-wei, Yue Hua, Xia Wia-bo, Luo Lian-mei, He Shu-li, Kiel Douglas P, Karasik David, Hsu Yi-Hsiang, Cupples L Adrienne, Demissie Serkalem, Styrkarsdottir Unnur, Halldorsson Bjarni V, Sigurdsson Gunnar, Thorsteinsdottir Unnur, Stefansson Kari, Richards J Brent, Zhai Guangju, Soranzo Nicole, Valdes Ana, Spector Tim D, Sham Pak C

Abstract excerpt

Bone mineral density (BMD), a diagnostic parameter for osteoporosis and a clinical predictor of fracture, is a polygenic trait with high heritability. To identify genetic variants that influence BMD in different ethnic groups, we performed a genome-wide association study (GWAS) on 800 unrelated S...

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Identifiers

PMID: 20096396
DOI: 10.1016/j.ajhg.2009.12.014
PMCID: PMC2820171

Genes

JAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20096396-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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