Article
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis.
Human molecular genetics - 15 Jan 2009
Johansson Asa, Marroni Fabio, Hayward Caroline, Franklin Christopher S, Kirichenko Anatoly V, Jonasson Inger, Hicks Andrew A, Vitart Veronique, Isaacs Aaron, Axenovich Tatiana, Campbell Susan, Dunlop Malcolm G, Floyd Jamie, Hastie Nick, Hofman Albert, Knott Sara, Kolcic Ivana, Pichler Irene, Polasek Ozren, Rivadeneira Fernando, Tenesa Albert, Uitterlinden André G, Wild Sarah H, Zorkoltseva Irina V, Meitinger Thomas, Wilson James F, Rudan Igor, Campbell Harry, Pattaro Cristian, Pramstaller Peter, Oostra Ben A, Wright Alan F, van Duijn Cornelia M, Aulchenko Yurii S, Gyllensten Ulf
Abstract excerpt
Genes for height have gained interest for decades, but only recently have candidate genes started to be identified. We have performed linkage analysis and genome-wide association for height in approximately 4000 individuals from five European populations. A total of five chromosomal regions showed suggestive linkage and in one of these regions, two SNPs (rs849140 and rs1635852) were associated with height...
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