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Article

Nucleocytoplasmic functions of the PDZ‐LIM protein family: new insights into organ development

20 Jan 2010

Abstract excerpt

Recent work on the PDZ-LIM protein family has revealed that it has important activities at the cellular level, mediating signals between the nucleus and the cytoskeleton, with significant impact on organ development. We review and integrate current knowledge about the PDZ-LIM protein family and propose a new functional role, sequestering nuclear factors in the cytoplasm. Characterized by their PDZ and LIM...

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PMID: 20091751
DOI: 10.1002/bies.200900148

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