Article
Experimental verification of a traceback phenomenon in prion infection.
Journal of virology - 1 Apr 2010
Kobayashi Atsushi, Sakuma Nobuyuki, Matsuura Yuichi, Mohri Shirou, Aguzzi Adriano, Kitamoto Tetsuyuki
Abstract excerpt
The clinicopathological phenotypes of sporadic Creutzfeldt-Jakob disease (sCJD) correlate with the allelotypes (M or V) of the polymorphic codon 129 of the human prion protein (PrP) gene and the electrophoretic mobility patterns of abnormal prion protein (PrP(Sc)). Transmission of sCJD prions to...
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