Article
[Extracellular mutant mitochondrial DNA content is sharply elevated in the blood plasma of irradiated mice].
Molekuliarnaia biologiia - 1 Jan 2000
Abdullaev S A, Antipova V N, Gaziev A I
Abstract excerpt
Nucleic acids circulating in blood plasma and other biological fluids may be of interest as potential markers for diagnosis of various pathologies and monitoring of stress influences. For many genotoxic agents, mitochondrial DNA (mtDNA) is a more vulnerable target than nuclear DNA, and mutations of mitochondrial genome may be markers of many diseases. In the present study extracellular mtDNA with mutations was...
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