Article
[Low efficiency of DNA repair system in mitochondria].
Tsitologiia - 1 Jan 2003
Gaziev A I, Podlutskiĭ A Ia
Abstract excerpt
Under the action of endogenous reactive oxygen species and exogenous chemical and physical agents, significantly more lesions occur in mitochondrial DNA (mtDNA) than in nuclear DNA (nDNA). However, the mechanisms of DNA repair in mitochondria are less efficient that in the nuclei. The mechanisms...
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