Article
[Role of polymorphous genes of xenobiotic biotransformation system in pathogenesis of occupational allergic dermatoses].
Meditsina truda i promyshlennaia ekologiia - 1 Jan 2011
Kuz'mina L P, Izmerova N I, Koliaskina M M
Abstract excerpt
Studying genetic polymorphism of xenogiotics biotransformation system genes in patients with occupational allergic dermatoses, the authors revealed reliably higher percentage of polymorphous variants of CYP 1A1 *2C and EPHX1 A-415G genes, if compared with reference population. Combination of 3 polymorphous variants of xenobiotics biotransformation system genes (CYP 1A1, CYP3A4, EPHX1, GSTM1 and GSTT1) is...
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