Article
[POLYMORPHISM OF GLUTHATIONE-S-TRANSFERASE P1 IN CHILDREN WITH REFLUX-ESOPHAGITIS].
Likars'ka sprava - 1 Jan 2000
Zagorskiy S E, Melnov S B, Sinevich E A
Abstract excerpt
The distribution of allele and genotype frequencies of genes of xenobiotic detoxication (CYP2E1--PstI, RsaI, DraI; ADH, ALDH, NAT2, GSTP1, GSTM1, GSTT1) was examined in 147 patients with reflux-esophagitis (RE) and 50 conditionally healthy children 12-18 years. The frequency of AA genotype of GSTP1 gene and A allele was significantly higher in patients with RE as compared with healthy children (χ2 = 4.93; P =...
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