Article
[Polymorphism of genes of the system of biotransformation of xenobiotics in patients with occupational allergic dermatoses].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2012
Izmerov N F, Kuz'mina L P, Koliaskina M M, Bezrukavnikova L M, Lazarashvili N A, Petinati Ia A
Abstract excerpt
Evaluation of genes polymorphic system of xenobiotics biotransformation in patients with occupational allergodermatoses showed significantly higher percentage of incidence of polymorphic variants of genes CYP 1A1 *2C and EPHX1 AND-415G compared with population control. A combination of 3 or more adverse hetero--and homozygous gene alleles CYP 1A1, CYP3A4, EPHX1 and deletions of genes GSTM1 and GSTT1, is...
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