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Article

Genetic predisposition to the development of congenital heart diseases: Role of xenobiotic biotransformation genes.

Birth defects research - 15 Apr 2021

Tsepokina Anna, Shmulevich Svetlana, Ponasenko Anastasia, Shabaldin Andrey

Abstract excerpt

Congenital heart diseases are one of the most common multi-factorial fetal abnormalities caused by a complex of endo- and exogenous factors. It is known that mutations in xenobiotic biotransformation genes can be associated with the pathogenesis of congenital heart diseases. In the presented research, 131 children with congenital heart diseases and 101 women having children with this pathology were included in...

Topics

Biotransformation
Child
Female
Genetic Predisposition to Disease
Glutathione S-Transferase pi
Heart Defects, Congenital
Humans
Xenobiotics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33174399
DOI: 10.1002/bdr2.1841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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