Article
Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk.
Human molecular genetics - 15 Sept 2009
Evans David M, Visscher Peter M, Wray Naomi R
Abstract excerpt
The current paradigm within genetic diagnostics is to test individuals only at loci known to affect risk of complex disease-yet the technology exists to genotype an individual at thousands of loci across the genome. We investigated whether information from genome-wide association studies could be harnessed to improve discrimination of complex disease affection status. We employed genome-wide data from the...
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