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Article

The effects of human population structure on large genetic association studies.

Nature genetics - 1 May 2004

Marchini Jonathan, Cardon Lon R, Phillips Michael S, Donnelly Peter

Abstract excerpt

Large-scale association studies hold substantial promise for unraveling the genetic basis of common human diseases. A well-known problem with such studies is the presence of undetected population structure, which can lead to both false positive results and failures to detect genuine associations....

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Source

Identifiers

PMID: 15052271
DOI: 10.1038/ng1337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15052271-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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