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Article

Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development

12 May 2017

Abstract excerpt

The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals brain lymphatics were only recently discovered, with significant implications for physiology and disease. We examined zebrafish for the presence of brain lymphatics and found loosely connected endothelial cells with lymphatic molecular signature covering parts of the brain without forming...

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PMID: 28498105
DOI: 10.7554/elife.25932

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