Article

Selective modulation of gene expression in activated normal human peripheral blood mononuclear cells by store-operated calcium entry blocker BTP2

2023-03-13

Abstract excerpt

Calcium is a critical signaling molecule in many cell types including immune cells. The calcium-release activated calcium channels (CRAC) responsible for store-operated calcium entry (SOCE) in immune cells are gated by STIM family members functioning as sensors of Ca 2+ store content in the endoplasmic reticulum. We investigated the effect of SOCE blocker BTP2 on human peripheral blood mononuclear cells (PBMC) sti...

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Literature Corpus work: a5e3e1b1-2cff-5b89-a4d2-f1ca678c1ea7
DOI: 10.21203/rs.3.rs-2618144/v1

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