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Article

An allosteric mechanism of Rho-dependent transcription termination.

Nature - 14 Jan 2010

Epshtein Vitaly, Dutta Dipak, Wade Joseph, Nudler Evgeny

Abstract excerpt

Rho is the essential RNA helicase that sets the borders between transcription units and adjusts transcriptional yield to translational needs in bacteria. Although Rho was the first termination factor to be discovered, the actual mechanism by which it reaches and disrupts the elongation complex (EC) is unknown. Here we show that the termination-committed Rho molecule associates with RNA polymerase (RNAP)...

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Identifiers

PMID: 20075920
DOI: 10.1038/nature08669
PMCID: PMC2929367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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