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Article

Embryonic Expression Suggests an Important Role for CRP2/SmLIM in the Developing Cardiovascular System

16 Nov 1998

Abstract excerpt

Proteins of the LIM family are critical regulators of development and differentiation in various cell types. We have described the cloning of cysteine-rich protein 2/smooth muscle LIM protein (CRP2/SmLIM), a LIM-only protein expressed in differentiated vascular smooth muscle cells. As a first step toward understanding the potential functions of CRP2/SmLIM, we analyzed its expression after gastrulation in...

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PMID: 9815145
DOI: 10.1161/01.res.83.10.980

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Embryonic Expression Suggests an Important Role for CRP2/SmLIM in the Developing Cardiovascular SystemPMID 9815145Read ↗

Comparison of three members of the cysteine-rich protein family reveals functional conservation and divergent patterns of gene expression.Semantic proximity Read ↗

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Identification of a CArG box-dependent enhancer within the cysteine-rich protein 1 gene that directs expression in arterial but not venous or visceral smooth muscle cells.Semantic proximity Read ↗

Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure.Semantic proximity Read ↗

MLP (muscle LIM protein) as a stress sensor in the heartSemantic proximity Read ↗

A cysteine-rich LIM-only protein mediates regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase.Semantic proximity Read ↗

The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone.Semantic proximity Read ↗

Serum response factor-dependent MicroRNAs regulate gastrointestinal smooth muscle cell phenotypes.Semantic proximity Read ↗

Transforming growth factor beta up-regulates cysteine-rich protein 2 in vascular smooth muscle cells via activating transcription factor 2.Semantic proximity Read ↗

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