Article
Optimization and validation of multi-coloured capillary electrophoresis for genotyping of Plasmodium falciparum merozoite surface proteins (msp1 and 2).
Malaria journal - 23 Apr 2009
Liljander Anne, Wiklund Lisa, Falk Nicole, Kweku Margaret, Mårtensson Andreas, Felger Ingrid, Färnert Anna
Abstract excerpt
BACKGROUND: Genotyping of Plasmodium falciparum based on PCR amplification of the polymorphic genes encoding the merozoite surface proteins 1 and 2 (msp1 and msp2) is well established in the field of malaria research to determine the number and types of concurrent clones in an infection. Genotyping is regarded essential in anti-malarial drug trials to define treatment outcome, by distinguishing recrudescent...
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