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Article

<i>ABL1</i> rearrangements in T‐Cell acute lymphoblastic leukemia

13 Jan 2010

Abstract excerpt

T-cell acute lymphoblastic leukemia (T-ALL) is the result of multiple oncogenic insults of thymocytes. Recently, new ABL1 fusion genes have been identified that provide proliferation and survival advantage to lymphoblasts. These are the NUP214-ABL1 fusion gene, on amplified episomes, the unique case of EML1-ABL1 fusion due to a cryptic t(9;14)(q34;q32) and the seldom reported BCR-ABL1 and ETV6-ABL1 chimeric...

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PMID: 20073070
DOI: 10.1002/gcc.20743

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