Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostically Significant Fusion Oncogenes in Pakistani Patients with Adult Acute Lymphoblastic Leukemia and their Association with Disease Biology and Outcome

31 Jul 2012

Abstract excerpt

BACKGROUND AND OBJECTIVES: Chromosomal abnormalities play an important role in genesis of acute lymphoblastic leukemia (ALL) and have prognostic implications. Five major risk stratifying fusion genes in ALL are BCR-ABL, MLL-AF4, ETV6-RUNX11, E2A-PBX1 and SIL-TAL1. This work aimed to detect common chromosomal translocations and associated fusion oncogenes in adult ALL patients and study their relationship with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Carcinogens and Genotoxicity Assessment
Share to Chronic Myeloid Leukemia Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22994759
DOI: 10.7314/apjcp.2012.13.7.3349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostically Significant Fusion Oncogenes in Pakistani Patients with Adult Acute Lymphoblastic Leukemia and their Association with Disease Biology and OutcomePMID 22994759Read ↗

Five Most Common Prognostically Important Fusion Oncogenes are Detected in the Majority of Pakistani Pediatric Acute Lymphoblastic Leukemia Patients and are Strongly Associated with Disease Biology and Treatment OutcomeSemantic proximity Read ↗

FREQUENCY OF THE MOST RECURRENT GENE FUSIONS IN ACUTE LYMPHOBLASTIC LEUKEMIA AMONG THE WORLD'S CONTINENTSSemantic proximity Read ↗

Clinico-biological features of T-cell acute lymphoblastic leukemia with fusion proteinsSemantic proximity Read ↗

New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemiaSemantic proximity Read ↗

Identification of Novel Fusion Genes in Pediatric B-ALL patients Using Whole Transcriptome SequencingSemantic proximity Read ↗

Identification of Novel Fusion Genes in Pediatric B-ALL patients Using Whole Transcriptome SequencingSemantic proximity Read ↗

Cytogenetics and Molecular Genetics in Pediatric Acute Lymphoblastic Leukemia (ALL) and Its Correlation with Induction OutcomesSemantic proximity Read ↗

PAX5 fusion genes in acute lymphoblastic leukemia: A literature review.Semantic proximity Read ↗

Low Incidence of ABL-Class And JAK-STAT Signaling Pathway Alterations In Uniformly Treated Pediatric And Adult B-Cell Acute Lymphoblastic Leukemia Patients Using MRD Risk-Directed Approach – A Population-Based StudySemantic proximity Read ↗

The Clinical and Genetic Features of ETV6/RUNX1-like Acute Lymphoblastic Leukemia in Pediatric: A Multicenter Retrospective StudySemantic proximity Read ↗

Clinical features, early treatment responses, and outcomes of pediatric acute lymphoblastic leukemia in china with or without specific fusion transcripts: A single institutional study of 1,004 patientsSemantic proximity Read ↗

Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.