Article
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
Neoplasia (New York, N.Y.) - 1 Jan 2010
Nakahara Yukiko, Northcott Paul A, Li Meihua, Kongkham Paul N, Smith Christian, Yan Hai, Croul Sidney, Ra Young-Shin, Eberhart Charles, Huang Annie, Bigner Darell, Grajkowska Wesia, Van Meter Timothy, Rutka James T, Taylor Michael D
Abstract excerpt
Although medulloblastoma is the most common pediatric malignant brain tumor, its molecular underpinnings are largely unknown. We have identified rare, recurrent homozygous deletions of Kruppel-like Factor 4 (KLF4) in medulloblastoma using high-resolution single nucleotide polymorphism arrays, dig...
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