Article
Transitioning from genotypes to epigenotypes: why the time has come for medulloblastoma epigenomics.
Neuroscience - 4 Apr 2014
Batora N V, Sturm D, Jones D T W, Kool M, Pfister S M, Northcott P A
Abstract excerpt
Recent advances in genomic technologies have allowed for tremendous progress in our understanding of the biology underlying medulloblastoma, a malignant childhood brain tumor. Consensus molecular subgroups have been put forth by the pediatric neuro-oncology community and next-generation genomic studies have led to an improved description of driver genes and pathways somatically altered in these subgroups. In...
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