Article
TIP47 is required for the production of infectious HIV-1 particles from primary macrophages.
Traffic (Copenhagen, Denmark) - 1 Apr 2010
Bauby Hélène, Lopez-Vergès Sandra, Hoeffel Guillaume, Delcroix-Genête Delphine, Janvier Katy, Mammano Fabrizio, Hosmalin Anne, Berlioz-Torrent Clarisse
Abstract excerpt
Macrophages are among the major targets of HIV-1 infection and play a key role in viral pathogenesis. Identification of the cellular cofactors involved in the production of infectious HIV-1 from macrophages is thus crucial. Here, we investigated the role of the cellular cofactor TIP47 in HIV-1 mo...
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