Macrophages and Cell-Cell Spread of HIV-1

doi:10.3390/v2081603

Article

Macrophages and Cell-Cell Spread of HIV-1

5 Aug 2010

Abstract excerpt

Macrophages have been postulated to play an important role in the pathogenesis of HIV-1 infection. Their ability to cross the blood-brain barrier and their resistance to virus-induced cytopathic effects allows them to serve as reservoirs for long-term infection. Thus, exploring the mechanisms of virus transmission from macrophages to target cells such as other macrophages or T lymphocytes is central to our...

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