Article
Reprogramming of anaerobic metabolism by the FnrS small RNA.
Molecular microbiology - 1 Mar 2010
Durand Sylvain, Storz Gisela
Abstract excerpt
Small RNAs (sRNAs) that act by base pairing with trans-encoded mRNAs modulate metabolism in response to a variety of environmental stimuli. Here, we describe an Hfq-binding sRNA (FnrS) whose expression is induced upon a shift from aerobic to anaerobic conditions and which acts to downregulate the levels of a variety of mRNAs encoding metabolic enzymes. Anaerobic induction in minimal medium depends strongly on FNR...
Topics
- Aerobiosis
- Anaerobiosis
- Bacterial Outer Membrane Proteins
- Base Pairing
- Base Sequence
- Conserved Sequence
- Culture Media
- Cyclic AMP Receptor Protein
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Profiling
- Gene Expression Regulation
- Host Factor 1 Protein
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Binding
- RNA, Small Interfering