From environmental signals to adaptive phenotypes: signal-responsive regulation and network logic of bacterial small RNAs.

doi:10.1093/femsre/fuag041

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Article

From environmental signals to adaptive phenotypes: signal-responsive regulation and network logic of bacterial small RNAs.

FEMS microbiology reviews - 2 Jan 2026

Yi Zhengkai, Xiao Xingning, Zou Likou, Cen Congnan, Shentu Xuping, Yu Xiaoping, Wang Wen

Abstract excerpt

Bacterial regulatory small RNAs (sRNAs) are integral components of posttranscriptional control, shaping environmental adaptation, metabolic homeostasis, and virulence. Advances in transcriptomics and RNA technologies have greatly expanded the repertoire of bacterial sRNAs and revealed their extensive roles in posttranscriptional regulatory networks. This review provides an updated framework for the biogenesis of...

Topics

Gene Expression Regulation, Bacterial
RNA, Bacterial
Bacteria
RNA, Small Untranslated
Adaptation, Physiological
Bacterial Physiological Phenomena
Phenotype
Signal Transduction
Gene Regulatory Networks

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Identifiers

PMID: 42606387
DOI: 10.1093/femsre/fuag041
PMCID: PMC13501541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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