Article
Shiga toxin of enterohemorrhagic Escherichia coli type O157:H7 promotes intestinal colonization.
Proceedings of the National Academy of Sciences of the United States of America - 20 Jun 2006
Robinson Cory M, Sinclair James F, Smith Michael J, O'Brien Alison D
Abstract excerpt
Enterohemorrhagic Escherichia coli (EHEC) 0157:H7 is a food-borne pathogen that can cause bloody diarrhea and, occasionally, acute renal failure as a consequence of Shiga toxin (Stx) production by the organism. Stxs are potent cytotoxins that are lethal to animals at low doses. Thus, Stxs not only harm the host but, as reported here, also significantly enhance the capacity of EHEC O157:H7 to adhere to epithelial...
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