Article
Genetic polymorphisms in the cytokine and chemokine system: their possible importance in allogeneic stem cell transplantation.
Current topics in microbiology and immunology - 1 Jan 2010
Loeffler Juergen, Ok Michael, Morton Oliver C, Mezger Markus, Einsele Hermann
Abstract excerpt
Chemokines represent central players of the innate and adaptive immunity and are involved in the regulation of inflammatory events occurring during infectious complications or during graft vs. host disease (GvHD). Patients after allogeneic stem cell transplantation (alloSCT) are at a high risk for the development of acute GvHD or to suffer from fungal infections. Susceptibility to fungal infections and the course...
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