Article
Association of IL-1β -511 polymorphism with severe veno-occlusive disease in pediatric-matched allogeneic hematopoietic stem cell transplantation.
Journal of pediatric hematology/oncology - 1 Apr 2012
Elbahlawan Lama, McArthur Jennifer, Quasney Michael W, Pei Deqing, Srivastava Kumar, Dahmer Mary K, Barfield Raymond
Abstract excerpt
Single nucleotide polymorphisms (SNPs) of the interleukin 1 (IL-1) family have been implicated in acute graft-versus-host disease and mortality postallogeneic hematopoietic stem cell transplantation (HSCT) in adults. Hepatic veno-occlusive disease (VOD) is a well-known complication of HSCT and can result in an increased risk of mortality. In this study, we sought to investigate the association of both patient and...
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