Article
Molecular evolution of the three short PGRPs of the malaria vectors Anopheles gambiae and Anopheles arabiensis in East Africa.
BMC evolutionary biology - 12 Jan 2010
Mendes Cristina, Felix Rute, Sousa Ana-Margarida, Lamego Joana, Charlwood Derek, do Rosário Virgílio E, Pinto João, Silveira Henrique
Abstract excerpt
BACKGROUND: Immune responses to parasites, which start with pathogen recognition, play a decisive role in the control of the infection in mosquitoes. Peptidoglycan recognition proteins (PGRPs) are an important family of pattern recognition receptors that are involved in the activation of these immune reactions. Pathogen pressure can exert adaptive changes in host genes that are crucial components of the vector's...
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