Article
Morphogen gradient formation.
Cold Spring Harbor perspectives in biology - 1 Sept 2009
Wartlick Ortrud, Kicheva Anna, González-Gaitán Marcos
Abstract excerpt
How morphogen gradients are formed in target tissues is a key question for understanding the mechanisms of morphological patterning. Here, we review different mechanisms of morphogen gradient formation from theoretical and experimental points of view. First, a simple, comprehensive overview of the underlying biophysical principles of several mechanisms of gradient formation is provided. We then discuss the...
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