Article
Studies of the effect of retinoic acid on anterior neural tube closure in mice genetically liable to exencephaly.
Teratology - 1 Jan 1991
Tom C, Juriloff D M, Harris M J
Abstract excerpt
Previously we have shown that all SELH/Bc mouse embryos close their anterior neural tubes by an abnormal mechanism and that 10-20% of SELH/Bc embryos are exencephalic. The purposes of these studies were (1) to observe the effects of retinoic acid on the frequency of exencephaly in SELH/Bc embryos; (2) to compare the SELH/Bc response with those of normal strains and of other neural tube mutants; and (3) to...
Topics
- Animals
- Embryo, Mammalian
- Female
- Genotype
- Gestational Age
- Mesencephalon
- Mice
- Mice, Inbred ICR
- Mice, Mutant Strains
- Neural Tube Defects
- Pregnancy
- Skull