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Article

Multifactorial genetics of exencephaly in SELH/Bc mice.

Teratology - 1 Oct 2001

Juriloff D M, Gunn T M, Harris M J, Mah D G, Wu M K, Dewell S L

Abstract excerpt

BACKGROUND: The SELH/Bc mouse strain has 10-30% exencephaly and is an animal model for human neural tube closure defects. This study examined the number of causative genes, their dominance relationships, and linkage map positions. METHODS: The SELH/Bc strain (S) was crossed to the normal LM/Bc strain (L) and frequencies of exencephaly were observed in the F(1), BC(1), and F(2) generations. 102 F(2) males were...

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Identifiers

PMID: 11598925
DOI: 10.1002/tera.1064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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