Article
Ataxia and a cerebellar defect in the exencephaly-prone SELH/Bc mouse stock.
Teratology - 1 Apr 1993
Juriloff D M, Harris M J, Harrod M L, Gunn T M, Miller J E
Abstract excerpt
SELH/Bc inbred mice have an abnormal mechanism of anterior neural tube closure and 10-20% of embryos have a lethal neural tube closure defect, exencephaly. Our previous studies have focused on this multifactorial threshold trait. However, SELH mice are also characterized by another trait that als...
Topics
- Animals
- Cerebellar Ataxia
- Cerebellum
- Female
- Genetic Predisposition to Disease
- Male
- Mice
- Mice, Inbred ICR
- Mice, Inbred Strains
- Neural Tube Defects
- Phenotype