Article
Noise in eukaryotic gene expression.
Nature - 10 Apr 2003
Blake William J, KAErn Mads, Cantor Charles R, Collins J J
Abstract excerpt
Transcription in eukaryotic cells has been described as quantal, with pulses of messenger RNA produced in a probabilistic manner. This description reflects the inherently stochastic nature of gene expression, known to be a major factor in the heterogeneous response of individual cells within a clonal population to an inducing stimulus. Here we show in Saccharomyces cerevisiae that stochasticity (noise) arising...
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