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Article

Chemical rescue of protein tyrosine phosphatase activity.

Chemical communications (Cambridge, England) - 28 Jan 2010

Chen Vincent L, Bishop Anthony C

Abstract excerpt

We report that the activity of a rationally engineered protein tyrosine phosphatase (PTP) mutant can be fully rescued by the addition of the biarsenical fluorescein derivative FlAsH, a compound that does not affect the activity of wild-type PTPs.

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Identifiers

PMID: 20062887
DOI: 10.1039/b919815f
PMCID: PMC2834275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20062887-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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