Article
Common genetic variation at 15q25.2 impacts on chronic lymphocytic leukaemia risk.
British journal of haematology - 1 Jul 2011
Crowther-Swanepoel Dalemari, Di Bernardo Maria Chiara, Jamroziak Krzysztof, Karabon Lidia, Frydecka Irena, Deaglio Silvia, D'Arena Giovanni, Rossi Davide, Gaidano Gianluca, Olver Bianca, Lloyd Amy, Broderick Peter, Laurenti Luca, Szemraj-Rogucka Zofia, Robak Tadeusz, Catovsky Daniel, Houlston Richard S
Abstract excerpt
A genome-wide association study of chronic lymphocytic leukaemia (CLL) suggested that common variants at 15q25.2 (rs783540) and 18q21.1 (rs1036935) influence CLL. To validate these associations and explore their relationship with CLL risk we genotyped case-control datasets from Poland, UK and Italy totalling 1428 cases and 1920 controls. Combined data from these and previously genotyped series (2503 cases and...
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