Replication-competent hybrids between murine leukemia virus and foamy virus.

doi:10.1128/jvi.77.13.7677-7681.2003

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Article

Replication-competent hybrids between murine leukemia virus and foamy virus.

Journal of virology - 1 Jul 2003

Shikova-Lekova Evelina, Lindemann Dirk, Pietschmann Thomas, Juretzek Thomas, Rudolph Wolfram, Herchenröder Ottmar, Gelderblom Hans R, Rethwilm Axel

Abstract excerpt

Replication-competent chimeric retroviruses constructed of members of the two subfamilies of Retroviridae, orthoretroviruses and spumaretroviruses, specifically murine leukemia viruses (MuLV) bearing hybrid MuLV-foamy virus (FV) envelope (env) genes, were characterized. All viruses had the cytoplasmic tail of the MuLV transmembrane protein. In ESL-1, a truncated MuLV leader peptide (LP) was fused to the complete...

Topics

Amino Acid Sequence
Animals
DNA, Viral
Humans
Hybridization, Genetic
Leukemia Virus, Murine
Molecular Sequence Data
Mutation
Spumavirus
Virus Replication

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Identifiers

PMID: 12805469
DOI: 10.1128/jvi.77.13.7677-7681.2003
PMCID: PMC164821

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